[Egrowth] Re: Egrowth Digest, Vol 7, Issue 1 (jawaban atas pertanyaan)

[Hermin Halim]

Bu Sekar, saya ingin coba menjawab pertanyaan tentang
gizi untuk penanganan logam berat, sejauh yang saya
ketahui ada beberapa makanan yang dapat digunakan
untuk mengurangi keracunan logam berat, terutama
makanan tinggi protein seperti susu dan telor. protein
dapat mengikat logam berat dan membentuk senyawa
kompleks yang nantinya dikeluarkan dari tubuh sehingga
mengurangi sifat racunnya.

artikel tentang penanganan logam berat dapat dicari di
www.ncbi.nlm.nih.gov/entrez/query.fcgi (Entrez-PubMed
USA) dan salah satu yang saya temukan adalah mengenai
pemberian suplemen kalsium. berdasarkan artikel ini,
pemenuhan gizi kalsium dapat mengurangi keracunan Pb
(timbal), tetapi pada pasien anak2 yang kebutuhan
kalsiumnya sudah terpenuhi, suplemen kalsium tidak
memberikan manfaat. berikut ini artikel selengkapnya.

Pediatrics. 2004 Jan;113(1 Pt 1):e34-9. 
  
A randomized trial of calcium supplementation for
childhood lead poisoning.

Markowitz ME, Sinnett M, Rosen JF.

Children's Hospital at Montefiore, Bronx, New York
10467, USA. markowit at aecom.yu.edu

OBJECTIVE: Lead (Pb) poisoning remains a common
disease among children despite successful public
health efforts that have reduced its prevalence.
Treatment options for children with blood Pb levels
(BPbs) <45 micro g/dL are limited because chelation
therapy is generally not indicated. Calcium (Ca) and
Pb interactions are well documented. Competition for
binding to Ca-binding proteins may underlie a
mechanism for Pb absorption. The purpose of this study
was to determine the role, if any, of supplemental Ca
at reducing BPbs in moderately poisoned children.
METHODS: Children aged 1 to 6 years with BPbs 10 to 45
micro g/dL were enrolled in a double-blinded,
placebo-controlled trial of the effects of Ca
supplementation on BPbs. Children received either a
Ca-containing liquid or an indistinguishable placebo.
Dosage was adjusted biweekly on the basis of responses
to a dietary Ca intake questionnaire to reach 1800 mg
in the Ca-supplemented group. Samples for BPbs and
measures to assess safety were collected before and
after 3 months of supplementation and after an
additional 3 months of follow-up. Bivariate and
multiple regression analyses were performed. RESULTS:
A total of 67 of 88 enrolled children with a mean age
of 3.6 years completed 3 months of supplementation.
There were no statistically significant differences
between groups on hematologic and biochemical
measures, including serum and urinary Ca, at any time
points. The average compliance rate was estimated to
be 80% for each group during the 3-month
supplementation period. CONCLUSIONS: At enrollment,
the average daily Ca intake in this group of
inner-city children was greater than the recommended
daily intake for age. Although BPbs declined during a
3-month period in both groups, Ca supplementation
aimed at providing 1800 mg of Ca/day had no effect on
the change in BPbs. Ca supplementation should not be
routinely prescribed for mild to moderately
Pb-poisoned children who are dietarily Ca sufficient.

Publication Types: 
Clinical Trial 
Randomized Controlled Trial 

PMID: 14702492 [PubMed - indexed for MEDLINE] 

semoga info ini bermanfaat, dan saya berharap akan ada
tambahan informasi dari ahli gizi/dietisien (terutama
dari Depkes :)))

salam,

hermin halim, apoteker


> Message: 1
> Date: Tue, 4 Jan 2005 21:53:58 -0500 (EST)
> From: "Jaringan Gizi Indonesia - Indonesian
> Nutrition Network"
> 	<info at gizi.net>
> Subject: [Egrowth] Re: informasi
> To: egrowth at gizi.net, skarla21 at yahoo.com
> Message-ID:
>
<65069.202.155.5.37.1104893638.squirrel at 202.155.5.37>
> Content-Type: text/plain;charset=iso-8859-1
> 
> Email anda kami forward. Tk
> 
> 
> > nama saya sekar, bekerja di LSM yang bergerak di
> bidang lingkungan,
> > khususnya masalah pencemaran logam berat, saya
> ingin minta bantuan apakah
> > ada artikel mengenai pemenuhan gizi dalam upaya
> mengurangi keracunan logam
> > berat....atau mungkin bisa memberikan contact
> person sehubungan dengan hal
> > tersebut.
> >
> > atas bantuannya, saya ucapkan banyak terima kasih
> >
> >
> > sekar
> >
> >
> > ---------------------------------
> > Do you Yahoo!?
> >  Yahoo! Mail - Easier than ever with enhanced
> search. Learn more.
> 
> 
> 
> 
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> 
> End of Egrowth Digest, Vol 7, Issue 1
> *************************************
> 


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